Nanobiotechnology is a rapidly developing field of research. Ever more applications are emerging from all branches of nanobiotechnology in medicine, pharmacy, cosmetics, chemical and agro-industry. The book presents the basics, fundamental results and latest achievements of nanobiotechnological research. It extends as far as promising applications of new nanomaterials and newly dicovered nanoeffects. Additionally, a large variety of nanobio-analysis methods is presented.
The book will appeal to graduate students, researchers and engineers.
Part I: Biological nano-objects.- 1. Structural and functional regulation of DNA: geometry, topology and methylation.- 2. Proteo-lipidic assembly and biomimetic nanostructures.- 3. Supramolecular complexes of DNA.- 4. Functionalized inorganic nanoparticles for biomedical applications.- 5. Living nanomachines.- 6. Aptamer selection by Darwinian evolution.- Part II: Methods of nanobiotechnology.- 7. Optical tools.- 8. Nanoforce and imaging.- 9. Surface methods.- 10. Mass spectrometry.- 11. Electrical characterization and dynamics of transport.- 12. Microfluidics: concepts and applications to the life sciences.- 13. Data processing.- 14. Molecular dynamics: observing matter in motion.- Part III: Applications of nanobiotechnology.- 15. Real-time PCR.- 16. Biosensors: from the glucose electrode to the biochip.- 17. DNA microarrays.- 18. Protein microarrays.- 19. Cell biochips.- 20. Lab on a chip.- 21. Polyelectrolyte multilayers.- 22. Biointegrating materials.- 23. Viral vectors for in vivo gene transfer.- 24. Pharmaceutical applications of nanoparticle carriers.- 25. Activatable nanoparticles for cancer treatment: nanobiotix.- 26. The medical, social, and economic stakes of nanobiotechnology.
Patrick Boisseau - Coordinator of the Nano2life European project - Specialist in Biotechnology-CEA
Philippe Houdy - University Professor of Physics of solids, Specialist in nanometric media and nanomaterials
Marcel Lahmani - Vice president of the French NanoMicrotechnology Club - Physicist and Docteur of Science
