§16§This comprehensive, ground-breaking title presents, in simplifying style, the driving and organizing principles of cancer, making this multidimensional, highly complex disease easily understandable for readers. Developed out of the renowned author's many years of teaching a widely popular, several-hundred-student college course, this 12-chapter book begins with an account of the history of cancer as a medical and public health problem, as well as the major milestones and setbacks in the ongoing quest to understand the wide variety of cancers that continue to impact the world. Subsequent chapters then address pathogenesis, incidence and mortality statistics, risk factors, causal factors, screening challenges and victories, treatment strategies, and disease prevention approaches. This wealth of clinical information is further supplemented with socioeconomic discussions on the financial, social, ethical, technological, regulatory, political, and logistical challenges thatlimit prog §16§ress in cancer research. A soon to be gold-standard text that thoroughly and expertly describes cancer as a composite, adaptive system, Cancer: The Enemy from Within equips and empowers all undergraduate students and graduate students to better understand this continually perplexing disease. Clinicians across all disciplines may also find this work of great interest.§ §04§Chapter 1. The Nature and Origins of Cancer.- Chapter 2. Cancer Initiation, Promotion and Progression and the Acquisition of Key Behavioral Traits.- Chapter 3. Understanding the Hallmark Characteristics of Cancer.- Chapter 4. A Short History of Cancer - How Did We Get Here? .- Chapter 5. Who Gets Cancer and Why? What Are the Consequences for Human Life and .-Longevity? How Can We Intervene? How Can We Track Progress?.- Chapter 6. Screening for Cancer: Find It Early; Treat It Early; Save Lives.- Chapter 7. Fundamentals of Cancer Diagnosis and Assessment.- Chapter 8. Local Therapy for Cancer.- Chapter 9. Systemic Therapy for Cancer.- Chapter 10. Palliative Care, Hospice, and End of Life.- Chapter 11. Development of New Cancer Therapies.- Chapter 12. Cancer and Society.§ §02§§Carolyn Compton, MD, PhD, FCAP§ §Professor of Life Sciences, Arizona State University§ §Barrett Honors Faculty, Arizona State University§ §Professor of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine§ §Adjunct Professor of Pathology, Johns Hopkins Medical Institutions§ §CMO, National Biomarker Development Alliance§ §Tempe, AZ 85281§ §USA§ § §04§toxicity; cost-benefit §§10. End of Life Issues: Personal and Medical §§Palliative care: what it is and how it is used §§Overuse of therapy at end of life §§Hard decisions: when to stop treatment § § §§11. Development of new cancer therapies: evolution and revolution §§The ethical, economic, and scientific aspects of translational cancer research §§Regulatory requirements §§The evolution of clinical trials § § §12. Cancer and society §§§Cancer and the law: Right to Die; Right to try §§Cancer as big business §§Economics of cancer care delivery: Who pays and for what? Who decides?§§§
