Researchers in a wide range of biological sciences and medical specialties examine the efflux systems that are the mechanism by which bacteria become resistant to antibiotics, and more generally to circumvent the effects of continuous exposure to antimicrobial stresses of which antibiotics are one example. They investigate how the microbes employ them to ensure their survival and establish and maintain successful infections. The topics include transmembrane molecular transporters facilitating export of molecules from cells and organelles, the machinery and mechanism of multi-drug efflux in Gram-negative bacteria, the role of efflux pumps in the nosocomial pathogens Staphylococcus aureus and Acinotobacter baumannii, Salmonella efflux pumps, and the function and regulation of Neisseria gonorrhoeae efflux pumps. Distributed in the US by ISBS. Annotation 2013 Book News, Inc., Portland, OR (booknews.com)
